I very much like my orgasms and having a hard time with the no ejaculation thing. The doctor gave me this first shot so I assume the inje, I am wondering if any men have experienced an almost total lack of spousal support and intimacy following your prostate cancer diagnosis and subsequent robotic nerve sparing radical prostatectomy. However, results are not optimum and resulting erecting is painful to the point that intercourses is not enjoyable. i was thinking of stocking up. During that time I have frozen the stuff, refrigerated it and left it at room temperature and have studied the results. Alprostadil lost 44% effectiveness at room temperature after 30 days. Room temperature exposure should be limited, and . Left at room temperature (22C), Trimix loses strength at 1% per day. I was aghast to read instructions saying that the drugs are good for only a month! Now I'm getting two different recommendations from two different Urologists.. Maybe they dont know since all individuals are different in their re, Hi - I just came back from my Urologist after taking my first shot of Trimix. Some comments recommend storing the drugs in a freezer, but the instructions say not to freeze them once they've been opened. im 48 and was diagnosed 3plus4 7 gleason, no escape from the prostate. erections and one terrified man!) Alprostadil lost 12.5% effectiveness at room temperature after seven days. this past January/18 for depression and regret at having had a prostatectomy and now no response, Been a month since leaving hospital and the fact that I had no nerve sparing the reality of ED is now hitting home. Testosterone (no ester) Suspension for Injection - Literature Review. I would also appreciate any female perspectives to this matter as well.My procedure was almost 3 years ago, and it was recommended that I have followup radiation. Welcome to ExcelMale.com, the leading and best-moderated mens health forum focused on increasing health, potency and productivity in men. Alprostadil can be frozen for six months with 95% effectiveness. At 34 weeks, the medication lost 25% and a 30% loss is seen after one full year at 41F. Stopped HCG, better libido and daily morning wood. At what Free T level do you feel optimal? This was highly effective in producing an erection but i, Hi everyoneI need opinions.. Need help understanding labs. The good news is, my PSA has b, Hello. also, i have no erectile response. For that I am happy and, Like many men who have had treatment for Prostate Cancer, I have had ED as a side effect. If there is a problem with long term room temperature storage, it is one of bacteriological contamination. After 20 weeks at 70F, a 37% loss was reported.. Prescribed Caverject Impulse alprostadil 10 micrograms injection. Refrigerated, Trimix loses strength at about 1% per week. Incontinence has not really been. Have questions about navigating your Inspire support community or need assistance from one of our Community Managers? After 3 months the first two fears are largely allayed. The short outdate is gift from the FDA (another stellar government agency). I have a question. I guess I'll try .2 cc next week. But what Im wondering is if PC recovery has changed how men experience orgasm. thanks in advance to all that reply.. So I am scared. Stage t1c. Today, I received the drugs and syringes from a compounding pharmacy. Told these are undectable? Now Im a 3+4 . When frozen, Trimix will last forever. 3. wow im surprised it would be that fast. I had 43 IMRT treatments that ended a year ago. Thankful I discovered this site to check out discussions that I would never have with my friends who have not had PC. Thinking about using injections but wanted some input before proceeding. When I spoke with the pharmacy, they said the formula had not changed, just the required outdate. This community is sponsored by ZERO - The End of Prostate Cancer, an Inspire trusted partner. Again, I don't recommend room temperature for more than two days. Inspire is dedicated to helping you connect with others and learn as you share stories. , Human Chorionic Gonadotropin (HCG) Pregnyl, Why you should not use testosterone cream, Interview with Dr. Rich Sagall of NeedyMeds.org. My father had prostate cancer 4 years ago at the age of 64. 2. ZERO - The End of Prostate Cancer Support Community. Testosterone Replacement, Low T, HCG, & Beyond, Penis Injections for Hard Erections: TRIMIX, Hormonal Approach for Postmenopausal Vulvovaginal Atrophy, Done with TRT and recovered within two weeks. I'm in good health and fit. Leaning toward prostatectomy. Now after a prostatectomy sex will never be the same again. There are a lot of posts on the ED issues and the quality of an erection. Due to my traveling I cant take the Injections on the road with me. However, I've seen a few comments online saying that the one-month instruction is CYA by the pharmacies and the drugs actually last much longer. JavaScript is disabled. You are using an out of date browser. Sidenafil and Cialis don't provide a firm erection. I am four months post robotic RP and am about to start Trimix injections. If you do not refrigerate Trimix, prostraglandin, the third ingredient will slowly degrade. What is one unexpected way a cancer diagnosis has impacted your life? Would any incontinence be endurable? Gleason score of 6. If the vial is stored in cotton wool soaked in isopropyl alcohol in a plastic zip bag, you shouldn't have a problem. Alprostadil lost 6% effectiveness under refrigeration after 30 days. I then put those in a sun glass case along with my injector thingy. i take viagra often with no effect. All lower left. It may not display this or other websites correctly. Because of my husband's young age and his strong family history every doctor we have seen has recommended RP. He has a Gleason score of a six. Gleason score of 6. 3. Was told that maybe wi, 4 months after RP, working to improve ED problems. he was diagnosed at 55. Bi-mix lasts even longer. The others 15-30 percent. I intend to keep using the vial as long as it works. Dealing with this has been a bigger adventure than I would like. A long time! I have kept trimix at room temperature for a week with no apparent loss of effectiveness. I am a 46 year old male. All Rights Reserved. Should I keep Tri-mix in the Refrigerator? I have been on the pecker power shots for over 25 years. The effectiveness will be reduced approximately 10% per day so adjust your dose accordingly. Its even a bit weird talking with my wife on some of these issues. My testosterone has returned to 300 so in the low normal range. I just sneak into the bathroom real quick, do my business and then get to business. 2. A beyond-use date of 6 months when stored frozen at -20 deg C and 1 month when stored refrigerated at 4 deg C is appropriate for batches of the injection that have passed sterility testing. I keep it refrigerated, used it successfully up to 18 months. I was hoping to hear from others who can give me their tho, Most of us have a partner and sex was a thing that we always did together. 2. I had 5 of 12 cores positive. Been using a pump for 3-4 months. Would all the cancer be removed? Urologist wanted to do removal surgery but I wasnt willing, so active surveillance for over 6 years now with 5 positive cores ( started with 2 ) out of 12 . Under refrigeration, it lost 6% potency after one month and 11% after two months. Daily Cialis didn't work. After reading on this site about pumps, got one and the results are similar. It could take me sometimes 2-3 weeks until it's time to refill. The doctor said at last visit when we ask how long should he take can stop whenever you feel you are ok. Well how do you know when you have taken enough, things could still improve, but guess that is typical advice from some docs. My husband has NEVER had ED. I'm disappointed as it only resulted in about a 60% erection. I wo, Dear members, Does anybody know what the real out-date is? For a better experience, please enable JavaScript in your browser before proceeding. Cialis had no affect what so ever. What kind of sexual satisfaction would be possible? 1 . Int J Pharm Compd. The one i am working on i keep in the fridge . I am 16 weeks post robotic surgery for prostate removal, aged 64, happily married to my wife for 39 years. I have visited a. However, that information will still be included in details such as numbers of replies. Dr. Stress, Sleep, and Testosterone with Dr. Abe Morgentaler, BPC-157 to guard against Cipro induced tendon damage, Higher libido & more frequent erections from Ibuprofen & caffeine. He adjusted it to 5 and it was almost as painful and then he went down to 4, missed the site and freaked us out (nothing happened of course) and then we had success a couple times. My urologist/surgeon prescribed Cialis 5mg daily beginning 2 weeks prior to surgery. Frozen, alprostadil lost less than 5% after six months.. So it would appear that those using Tri-mix could, when traveling, leave it. Any advice. My husband has been on Sildenafil 20 mg for almost a year since his Robotic prostatectomy. I keep them in there unrefrigerated until I run out. 2004 May-Jun;8(3):231-5. Initially, I experienced a 9 out of 10 erection(4hr. I'm about to start Trimix injections to solve a problem worsened by radiation treatments for prostate cancer. The good news is, after three PSA tests since the completion of my treatments, my PSA has remained below .1. I know its largely unknown how or if and how much of any ED or incontinence one is likely to have based on your surgeon, anatomy, and how well you recover. Currently on clomid. Kept cold(not frozen), I don't think it really goes bad. At 2 weeks, I have noticed trimix is less effective. Not enough for penetration. 12Mg of Cypionate causing so many side effects? I am recently married to, As I shared before the first time my husband did the injection at 10 in the office his erection was painful and lasted a little over 2 hours. Refrigerated, Trimix loses strength at about 1% per week. He is scheduled for surgery on Dec. 2nd. My oncologist says there is nothing to do at this point but keep checking every 4 months or so. Being a relatively young 56 in PC terms I'm concerned about the impact this will have on my life. 3. How long is trimix good for if kept refrigerated? Can lowering cholesterol cause low testosterone? I prefill 20 syringes at a time. A brief history: Papaverine and phentolamine , (two of the 3 ingredients in Trimix), can be kept at room temperature and won't degrade that much. You can tell no difference between the first shot and the last. In reading online, I noticed that, while the three components seem to always be the same, the amounts/concentrations are not and can be variable. No incontenience but struggling with erections. No previous history of sexual dysfunction. I have used refrigerated syringes of Trimix up to 6 months with good results. After RP: Does anyone NOT suffer from ED. His Father had it as well around the same age as him, so I am the youngest in the family to get it. Frozen at -20 deg C and -70 deg C, less than 5% loss of any of the drug componnets occurred in 6 months. He said he would start off with a low dose of .15 cc . I had to increase my dose, but I used it for 9 months! A couple of years ago I went overseas and stayed for 7 weeks in countries mostly without fridges in hotel rooms and therefore there was no refrigeration for most that time. with 10 units of Prostin(last October) but fast forward to this past June and having been prescribed Mirtazapine(Remeron)45mgs. Even if previously you never used to 'pleasure yourself' it is important that you should start now! Stored in a syringe, alprostadil lost 10% effectiveness at 41F (refrigeration) after 24 weeks. Has any one had a similar experience and if so, what happened when you upped the does? He gets rock hard when the, Well it's been 6 months since my RPS and first PSA .10 and second .05. My father had radiation and is doing well. Also by prefilling the syringes it'd less intrusive on the moment. I bought one of those pump things and it was simply ineffective and painful. After 7 weeks I needed to increase the dose by about 70%, but it worked well at that dosage. Well I would like to say I use 20 of them in a few days but I am no spring chicken lol. Now the urologist says I should do the seed implant. Not just about the cancer but if the side effects. Have my follow-up with my oncologist in a week or so. As I'm a few weeks from my 80th birthday, there's no way I can use enough of it to make the cost per injection worthwhile. Anyone use MUSE Urethral Suppositories in their rehab program? Are you sure you want to block this member? A. This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register. Does anybody know if they can in fact be re-frozen? Today we are beginning a partnership with The Mighty, a publisher of stories by and about people facing medical challenges. I keep it frozen all time ,I let melt draw a shot put Bach in freezer. I was recently diagnosed. The Case Against Coronary Artery Calcium Scoring for Cardiovascular Disease Risk Assessment. bimix shots work great but i was hoping for a return of erectile function. Been taking 2 tabs of Viagra daily. My dad had very aggressive PC that spread to lymph-nodes. Basically, regardless of what pharmaceutical authorities tell you, the story is this : 1. I knew t, i am almost four months post robotic surgery. Expert opinion suggests that ED sufferers need to get at least three erections a week. 2. I have been using trimix for about 4 years now.. undefined will no longer be visible to you including posts, replies, and photos. That was a couple months ago. i have used the trimix up to 60 days after thawing. Alprostadil lost 2% effectiveness under refrigeration after seven days. My urologist/surgeon prescribed Tri-mix Super Mayo at 3 months after RRP. If the vial is stored in cotton wool soaked in isopropyl alcohol in a plastic zip bag, you shouldn't . If there is a problem with long term room temperature storage, it is one of bacteriological contamination. Together we are launching a campaign to shed light on this question: What is one unexpected way a cancer diagnosis has impacted your, I was diagnosed 2/5/16 at 54 years old . Find other members in this community to connect with. One has recommended the penile pump .. For a short, weekend trip, they are advised to draw up their syringe at about 1.25 times their normal dose and keep it at no more than room temperature (70F). His brother is 14 years older and has stage 4 PC. Since my RRP in March, I've had no luck at all when it comes to recovering sexual function with regard to achieving erections. Gleason score 6 3+3 with a psa of 4.5 . I have been using Trimix for four and a half years and have had a total of 800 injections. At 70F (room temperature), alprostadil losts 10% effectiveness after 6 weeks. Surgeon said he spared the nerves but I'm wondering if that was really the case. It's not over just different. Hope that helps ease your concerns Roger. Since then the erections have not been 100%, 9/6/18: Diagnosed with prostate cancer after biopsy. To be honest, I cannot imagine interc, Anyone ever experience a contraindication with any mixture used for injection therapy? Viagra didn't work. The other is recommending going straight to injections.. 9/26/18: Over the past few weeks, it has been recommended to me by 3 dif, Hi We are a very sexually active couple. My preparation has these concentrations: PGE1 (8.3 mcg/ml); Phentolamine (0.8 mg/ml); Papaverine (22.5 mg/ml).Is that similar to what others are using?Thank. I found a bottle way back in the Refrigerator that is 3 years old (per mix).. By any chance would that bottle still be at any use or good? usually its at the end of day or when tired etc. Hi - I was wondering if anyone out there has any experience with using a pump for ED after treatment for prostate cancer. Going to give nebido another shot! Dr felt it before the biopsy. I have been using the same vial for more than two years (I don't use a lot, or need it every time). I freeze the vial that is not yet being used. i have had 4 biopsies during This time and psa has crept up to 8.6 . 1. Alprostadil lost 8% potency in five days at room temperature. I have a Gleason 3+4 = 7 and looking at the options. So heres something Id like some feedback on. Here is what I do and works great. I had three fears: Still trying to get a second opinion. All treatment and consults at Mt Sinai in NY. No problem with administering and no pain. 2 of the votes were 40-60%. Left at room temperature (22C), Trimix loses strength at 1% per day. my tw, I was advised today by my urologist that my ED is caused by tissue or nerve damage from my treatment which was 3 months of ADT (Firmagon), External Beam radiation plus brachytherapy completed July 2015. I use Bi-mix -- I keep it in the freezer and just thaw it out long enough to draw a few syringes which I then keep in the refrigerator for use. There's hang on hunny while I fill my syringes and shoot up lol. Previously any male had 7 or 8 spontaneous, My husband is 52 years old and was diagnosed with stage one PC in June. i am still dripping enough to have to wear a light pad and feel gross. Nobody knows my secret if I don't want them too. The ZERO - The End of Prostate Cancer Support Community connects patients, families, friends and caregivers to enhance the quality of life for all those affected by prostate cancer.

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